Wood (5-12) ended an eight-game skid of his own, striking out five and walking three to win for the first time in more than two months.
Starlin Castro had three hits, including the 500th of his career, and drove in four runs for the Cubs. Alfonso Soriano added three hits and three RBI as Chicago took full advantage of one of the worst defensive nights in Pittsburghâs 130-year history.
The Pirates had not made seven errors in a game since 1985 and finished one shy of the club record set in 1939. It was the first seven-error game in the majors since Atlanta in a 2004 loss to Colorado.
He struck out four and walked one.
On a night the Pirates seemed to be far from a postseason contender, Pittsburghâs problems started early and never stopped.
The Cubs used an error by rookie second baseman Brock Holt to take a 1-0 lead in the first before things really got out of hand a couple innings later.
Chicago made it 4-0 in the third with plenty of help from left fielder Starling Marte. The rookie, activated from the disabled list earlier in the day, mishandled a single by Soriano with one on and two outs. The ball caromed off his glove away from him and in his haste to recover, Marte fired wildly in the vicinity of third base. The ball sailed all the way to the backstop, allowing Anthony Rizzo and Soriano to move into scoring position. Moments later Marte was in trouble again when he booted a sharply hit ball by Castro.
Pittsburgh manager Clint Hurdle tried to give his team some life, getting ejected for the fourth time this season for arguing a close play at third base in which umpire Gary Darling ruled Chicagoâs Brett Jackson beat Josh Harrisonâs throw on a fieldersâ choice.
The Pirates responded by allowing three more runs thanks in part to throwing errors by first baseman Gaby Sanchez and catcher Rod Barajas. Two more errors in the seventh helped the Cubs push the lead to 12-0.
At one point a fan in an exasperated PNC Park crowd started yelling âerror! error!â at the official scorer on a cleanly hit single by Chicagoâs Tony Campana in the eighth.
Instead of history, the Pirates finished with only seven errors, the most since an 8-4 loss to St. Louis on Sept. 16, 1985.
Wood, who hadnât won since beating the Mets on July 6, didnât let the good fortune go to waste. He retired 14 of the first 15 batters he faced and didnât give up a hit until the fifth when Pedro Alvarezâs flyball to center glanced off Jacksonâs glove as the outfielder smacked into the wall.
Castro became the 28th player in major league history to reach 500 hits before his 23rd birthday. The previous player to do it was Alex Rodriguez ... Jackson left after sixth inning with a bruised knee sustained when he crashed into the fence while running down a flyball by Pittsburghâs Andrew McCutchen. Jackson laid on the ground for several minutes before slowly walking off the field ... The series continues on Saturday. Chicagoâs Jeff Samardzija (8-13, 3.91 ERA) will make his final start of the season for the Cubs against Pittsburghâs James McDonald (12-7, 3.90).